Neuroscience

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(2014) Regulatory mechanisms underlying the differential growth of dendrites and axons

Media:2014_--_Regulatory_mechanisms_underlying_the_differential_growth_of_dendrites_and_axons.pdf

"Recent studies have uncovered two distinct types of regulatory mechanisms that differentiate dendritic and axonal growth: dedicated mechanisms and bimodal mechanisms. Dedicated mechanisms regulate either dendrite- specific or axon-specific growth; in contrast, bimodal mechanisms direct dendritic and axonal development in opposite manners."
[1]


Shrooms

Potentiation of neuritogenic activity of medicinal mushrooms in rat pheochromocytoma cells

ShroomPathways.png


DIHEXA

Media:The pro-cognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor-c-Met system.pdf

Ashwagandha

Axon (or dendrite) predominant outgrowth induced by constituents from Ashwagandha

"results suggest that axons are predominantly extended by withanolide A, and dendrites by withanosides IVand VI."

Media:2002_--_Axon-_or_dendrite-predominant_outgrowth_induced_by_constituents_from_Ashwagandha.pdf


(2009) Sominone enhances neurite outgrowth and spatial memory mediated by the neurotrophic factor receptor, RET

withanoside IV a.k.a. Sominone = GDNF-independent stimulator of the RET pathway and/or a novel modulator of RET signalling